Dong Xiao Selected Research

pregna-4,17-diene-3,16-dione (guggulsterone)

6/2014	Retracted: Guggulsterone inhibits prostate cancer growth via inactivation of Akt regulated by ATP citrate lyase signaling.
8/2013	Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.
3/2011	Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.
1/2008	z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo.
8/2007	Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase.
11/2005	Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak.

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Dong Xiao Research Topics

Disease

62	Neoplasms (Cancer) 06/2021 - 07/2002
32	Prostatic Neoplasms (Prostate Cancer) 05/2022 - 07/2002
7	Breast Neoplasms (Breast Cancer) 04/2018 - 11/2006
6	Neoplasm Metastasis (Metastasis) 01/2021 - 11/2008
6	Nasopharyngeal Carcinoma 01/2020 - 02/2013
5	Sepsis (Septicemia) 03/2022 - 04/2015
5	Carcinogenesis 11/2021 - 03/2009
5	Squamous Cell Carcinoma of Head and Neck 01/2021 - 10/2003
5	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 10/2004
3	Septic Shock (Toxic Shock Syndrome) 02/2022 - 03/2012
3	Lung Neoplasms (Lung Cancer) 01/2020 - 04/2009
3	Adenocarcinoma 02/2014 - 04/2005
3	Flushing 01/2012 - 10/2008
3	Carcinoma (Carcinomatosis) 03/2009 - 07/2002
2	Infections 05/2022 - 04/2017
2	Acute Kidney Injury (Acute Renal Failure) 03/2022 - 02/2020
2	Disease Resistance 01/2021 - 08/2020
2	Hemorrhage 01/2021 - 10/2008
2	HIV Infections (HIV Infection) 10/2020 - 01/2014
2	Diabetes Complications 04/2020 - 06/2014
2	Diabetic Nephropathies (Diabetic Nephropathy) 04/2020 - 01/2017
2	Laryngeal Neoplasms (Laryngeal Cancer) 10/2019 - 01/2019
2	Glioma (Gliomas) 01/2019 - 01/2019
2	Colorectal Neoplasms (Colorectal Cancer) 01/2018 - 04/2007
2	Coinfection 04/2017 - 01/2012
2	Inflammation (Inflammations) 04/2015 - 02/2013
2	Pneumothorax 04/2013 - 10/2008
2	Dyslipidemias (Dyslipidemia) 01/2012 - 02/2011
2	Emphysema 03/2011 - 10/2008

Drug/Important Bio-Agent (IBA)

17	Proteins (Proteins, Gene)FDA Link 03/2022 - 10/2003
11	phenethyl isothiocyanate (PEITC)IBA 08/2010 - 07/2002
11	diallyl trisulfideIBA 06/2010 - 07/2004
10	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2014 - 05/2005
7	Long Noncoding RNAIBA 01/2021 - 01/2019
6	pregna-4,17-diene-3,16-dione (guggulsterone)IBA 06/2014 - 11/2005
5	CytokinesIBA 03/2022 - 04/2015
5	Biomarkers (Surrogate Marker)IBA 06/2021 - 07/2013
5	Phosphotransferases (Kinase)IBA 12/2012 - 07/2002
5	benzyl isothiocyanateIBA 01/2012 - 10/2003
5	AndrogensIBA 03/2011 - 05/2003
5	sulforaphaneIBA 07/2009 - 01/2004
4	Messenger RNA (mRNA)IBA 03/2022 - 10/2004
4	AntigensIBA 06/2021 - 05/2005
4	InterferonsIBA 01/2020 - 01/2012
4	CateninsIBA 06/2019 - 08/2013
4	Pharmaceutical PreparationsIBA 09/2016 - 02/2014
4	Peptides (Polypeptides)IBA 09/2016 - 02/2014
4	JNK Mitogen-Activated Protein KinasesIBA 06/2014 - 07/2004
4	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 07/2012 - 07/2002
3	EnzymesIBA 05/2022 - 07/2014
3	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 10/2016
3	BerberineIBA 04/2020 - 12/2012
3	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2020 - 04/2009
3	Adenosine Triphosphate (ATP)IBA 09/2019 - 12/2012
3	MicroRNAs (MicroRNA)IBA 01/2019 - 02/2013
3	LuciferasesIBA 01/2018 - 10/2015
3	DNA (Deoxyribonucleic Acid)IBA 07/2017 - 01/2004
3	Silicon Dioxide (Silica)FDA LinkGeneric 09/2016 - 02/2014
3	DisulfidesIBA 09/2016 - 02/2014
3	CaspasesIBA 03/2006 - 01/2004
2	FlavonoidsIBA 05/2022 - 01/2003
2	LipopolysaccharidesIBA 03/2022 - 11/2021
2	GalactosamineIBA 03/2022 - 11/2021
2	BilirubinIBA 03/2022 - 01/2021
2	Mitogen-Activated Protein KinasesIBA 03/2022 - 07/2005
2	CarbohydratesIBA 06/2021 - 01/2020
2	Competitive Endogenous RNAIBA 01/2021 - 01/2019
2	Antisense RNA (Anti-Sense RNA)IBA 01/2021 - 01/2019
2	Blood Glucose (Blood Sugar)IBA 10/2020 - 10/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 02/2013
2	Hematoxylin (Haematoxylon)IBA 09/2019 - 01/2019
2	Eosine Yellowish-(YS) (Eosin)IBA 09/2019 - 01/2019
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2018 - 04/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 04/2017 - 03/2012
2	ProcalcitoninIBA 04/2017 - 04/2015
2	Estrogen ReceptorsIBA 12/2016 - 08/2013
2	Glutathione (Reduced Glutathione)IBA 09/2016 - 02/2014
2	InterleukinsIBA 04/2015 - 02/2013
2	ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA 07/2014 - 06/2014
2	Cyclin D1IBA 08/2013 - 07/2012
2	guggulu extractIBA 08/2013 - 03/2011
2	Niacin (Nicotinic Acid)FDA LinkGeneric 01/2012 - 02/2011
2	CarbonIBA 01/2012 - 10/2003
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2010 - 03/2007
2	Checkpoint Kinase 1IBA 11/2009 - 04/2007
2	diallyl disulfide (diallyl disulphide)IBA 04/2009 - 07/2004
2	allyl sulfideIBA 04/2009 - 07/2004
2	Apoptosis Regulatory ProteinsIBA 04/2009 - 10/2003
2	Cyclin B1IBA 04/2007 - 10/2003
2	IsothiocyanatesIBA 10/2003 - 05/2003
2	2,3,4-tri-O-acetylarabinopyranosyl isothiocyanate (AITC)IBA 10/2003 - 05/2003
2	allyl isothiocyanateIBA 10/2003 - 05/2003

Therapy/Procedure

10	Therapeutics 01/2021 - 01/2004
3	Critical Care (Surgical Intensive Care) 02/2022 - 03/2012
3	Lung Transplantation 03/2011 - 05/2006
2	Ligation 09/2019 - 12/2012
2	Intravenous Infusions 03/2016 - 10/2015
2	Ayurvedic Medicine (Siddha Medicine) 08/2013 - 03/2011
2	Pneumonectomy (Lung Volume Reduction) 04/2013 - 05/2006
2	Oral Administration 04/2010 - 04/2005